NHG-Standaard
M103
3.1
In herziening
augustus 2022
december 2024
K. Hart-vaatstelsel

Richtlijnen diagnostiek

Naar Volledige tekst ›

Eerste (telefonische) contact

Naar Volledige tekst ›

ABCDE stabiel

Naar Volledige tekst ›

Lichamelijk onderzoek

Naar Volledige tekst ›

Aanvullend onderzoek

Naar Volledige tekst ›

Richtlijnen beleid acute fase

Naar Volledige tekst ›

Uitvalsverschijnselen aanwezig, < 12 uur geleden ontstaan (U1, spoed)

Naar Volledige tekst ›

Uitvalsverschijnselen aanwezig, ≥ 12 uur geleden ontstaan (U2, < 1 uur)

Naar Volledige tekst ›

Uitvalsverschijnselen aanwezig: infauste prognose of wens thuis te blijven (U2, < 1 uur)

Naar Volledige tekst ›

Uitvalsverschijnselen volledig verdwenen (U3, binnen enkele uren)

Naar Volledige tekst ›

Richtlijnen beleid na ontslag

Naar Volledige tekst ›

Overdracht van tweede lijn naar huisarts

Naar Volledige tekst ›

Aandachtspunten

Naar Volledige tekst ›

Medicamenteuze onderhoudsbehandeling

Naar Volledige tekst ›

Consultatie en verwijzing

Naar Volledige tekst ›

Belangrijkste wijzigingen

Naar Samenvatting ›

Kernboodschappen

Naar Samenvatting ›

Achtergronden

Naar Samenvatting ›

Epidemiologie

Naar Samenvatting ›

Etiologie en pathofysiologie

Naar Samenvatting ›

TIA en herseninfarct

Naar Samenvatting ›

Intracerebrale bloeding

Naar Samenvatting ›

Beloop en prognose

Naar Samenvatting ›

Restverschijnselen

Naar Samenvatting ›

Neuropsychologische functiestoornissen na herseninfarct of intracerebrale bloeding

Naar Samenvatting ›

Neuropsychologische functiestoornissen na TIA

Naar Samenvatting ›

Behandelingsmogelijkheden

Naar Samenvatting ›

Opname op een stroke unit

Naar Samenvatting ›

Intraveneuze trombolyse

Naar Samenvatting ›

Endovasculaire behandeling

Naar Samenvatting ›

Secundaire preventie

Naar Samenvatting ›
Carotisdesobstructie
Naar Samenvatting ›

Revalidatie na herseninfarct of intracerebrale bloeding

Naar Samenvatting ›
Oefen- en ergotherapie
Naar Samenvatting ›

Richtlijnen diagnostiek

Naar Samenvatting ›

Eerste (telefonische) contact

Naar Samenvatting ›
FAST-test (Face-Arm-Speech-Time-test)
Naar Samenvatting ›

Lichamelijk onderzoek

Naar Samenvatting ›

Aanvullend onderzoek

Naar Samenvatting ›

Predictiemodel

Naar Samenvatting ›
Acuut dubbelzien
Naar Samenvatting ›

Richtlijnen beleid acute fase

Naar Samenvatting ›

Uitvalsverschijnselen aanwezig, < 12 uur geleden ontstaan (U1, spoed)

Naar Samenvatting ›

Uitvalsverschijnselen aanwezig, ≥ 12 uur geleden ontstaan (U2, < 1 uur)

Naar Samenvatting ›

Uitvalsverschijnselen aanwezig: infauste prognose of wens thuis te blijven (U2, < 1 uur)

Naar Samenvatting ›

Uitvalsverschijnselen volledig verdwenen (U3, binnen enkele uren)

Naar Samenvatting ›
ABCD²-score
Naar Samenvatting ›

Richtlijnen beleid na ontslag

Naar Samenvatting ›

Overdracht van tweede lijn naar huisarts

Naar Samenvatting ›

Aandachtspunten

Naar Samenvatting ›

Behandeling

Naar Samenvatting ›
Barthelindex
Naar Samenvatting ›
Neuropsychologisch
Naar Samenvatting ›

Maatschappelijk functioneren

Naar Samenvatting ›

Voorlichting

Naar Samenvatting ›
Leefstijladviezen
Naar Samenvatting ›

Rijgeschiktheid

Naar Samenvatting ›

Seksualiteit

Naar Samenvatting ›

Medicamenteuze onderhoudsbehandeling

Naar Samenvatting ›

Na TIA of herseninfarct

Naar Samenvatting ›
Trombocytenaggregatieremmers
Naar Samenvatting ›
Orale anticoagulantia
Naar Samenvatting ›
Cholesterolverlagende medicatie
Naar Samenvatting ›
Antihypertensiva
Naar Samenvatting ›
Beleid na een herseninfarct als gevolg van arteriële dissectie
Naar Samenvatting ›

Na een intracerebrale bloeding

Naar Samenvatting ›
Trombocytenaggregatieremmers
Naar Samenvatting ›
Anticoagulantia
Naar Samenvatting ›
Antihypertensiva
Naar Samenvatting ›
Cholesterolverlagende medicatie
Naar Samenvatting ›

Consultatie en verwijzing

Naar Samenvatting ›

CVA ketenzorg

Naar Samenvatting ›

Referenties

  1. Easton JD, Saver JL, Albers GW, Alberts MJ, Chaturvedi S, Feldmann E, et al. Definition and evaluation of transient ischemic attack: a scientific statement for healthcare professionals from the American Heart Association/American Stroke Association Stroke Council; Council on Cardiovascular Surgery and Anesthesia; Council on Cardiovascular Radiology and Intervention; Council on Cardiovascular Nursing; and the Interdisciplinary Council on Peripheral Vascular Disease. The American Academy of Neurology affirms the value of this statement as an educational tool for neurologists. Stroke 2009;40:2276-93.
  2. Mendelson SJ, Prabhakaran S. Diagnosis and Management of Transient Ischemic Attack and Acute Ischemic Stroke: A Review. Jama 2021;325:1088-98.
  3. Sacco RL, Kasner SE, Broderick JP, Caplan LR, Connors JJ, Culebras A, et al. An updated definition of stroke for the 21st century: a statement for healthcare professionals from the American Heart Association/American Stroke Association. Stroke 2013;44:2064-89.
  4. Hartstichting. Hart- en vaatziekten in Nederland 2020: cijfers over risicofactoren, hartinterventies, ziekte en sterfte. (2020). Geraadpleegd mei 2022. Ga naar bron: Hartstichting. Hart- en vaatziekten in Nederland 2020: cijfers over risicofactoren, hartinterventies, ziekte en sterfte. (2020). Geraadpleegd mei 2022.
  5. Nielen MM, Hek K, Schermer TR. Jaarcijfers aandoeningen: incidenties en prevalenties. (2021). Geraadpleegd mei 2022. Ga naar bron: Nielen MM, Hek K, Schermer TR. Jaarcijfers aandoeningen: incidenties en prevalenties. (2021). Geraadpleegd mei 2022.
  6. Vaartjes I, O'Flaherty M, Capewell S, Kappelle J, Bots M. Remarkable decline in ischemic stroke mortality is not matched by changes in incidence. Stroke 2013;44:591-7.
  7. Bos V, Kunst AE, Keij-Deerenberg IM, Garssen J, Mackenbach JP. Ethnic inequalities in age- and cause-specific mortality in The Netherlands. Int J Epidemiol 2004;33:1112-9.
  8. Agyemang C, Addo J, Bhopal R, De Graft Aikins A, Stronks K. Cardiovascular disease, diabetes and established risk factors among populations of sub-Saharan African descent in Europe: a literature review. Global Health 2009;5:7.
  9. Alter M. Black-white differences in stroke frequency: challenges for research. Neuroepidemiology 1994;13:301-7.
  10. Broderick JP, Brott T, Tomsick T, Huster G, Miller R. The risk of subarachnoid and intracerebral hemorrhages in blacks as compared with whites. N Engl J Med 1992;326:733-6.
  11. Reeves MJ, Bushnell CD, Howard G, Gargano JW, Duncan PW, Lynch G, et al. Sex differences in stroke: epidemiology, clinical presentation, medical care, and outcomes. Lancet Neurol 2008;7:915-26.
  12. RIVM. 30-dagen sterfte na acuut myocardinfarct of beroerte (2011).
  13. Petrea RE, Beiser AS, Seshadri S, Kelly-Hayes M, Kase CS, Wolf PA. Gender differences in stroke incidence and poststroke disability in the Framingham heart study. Stroke 2009;40:1032-7.
  14. Lisabeth LD, Brown DL, Hughes R, Majersik JJ, Morgenstern LB. Acute stroke symptoms: comparing women and men. Stroke 2009;40:2031-6.
  15. Stuart-Shor EM, Wellenius GA, DelloIacono DM, Mittleman MA. Gender differences in presenting and prodromal stroke symptoms. Stroke 2009;40:1121-6.
  16. Persky RW, Turtzo LC, McCullough LD. Stroke in women: disparities and outcomes. Curr Cardiol Rep 2010;12:6-13.
  17. Dirks M, Niessen LW, Van Wijngaarden JDH, Koudstaal PJ, Franke CL, Van Oostenbrugge RJ, et al. Promoting thrombolysis in acute ischemic stroke. Stroke 2011;42:1325-30.
  18. Rothwell PM, Coull AJ, Giles MF, Howard SC, Silver LE, Bull LM, et al. Change in stroke incidence, mortality, case-fatality, severity, and risk factors in Oxfordshire, UK from 1981 to 2004 (Oxford Vascular Study). Lancet 2004a;363:1925-33.
  19. Franke CL, Poos MJJC, Van Wieren S. Hoeveel zorg gebruiken patiënten met beroerte en wat zijn de kosten? Nationaal Kompas Volksgezondheid. (2011b).
  20. Jones SP, Bray JE, Gibson JM, McClelland G, Miller C, Price CI, et al. Characteristics of patients who had a stroke not initially identified during emergency prehospital assessment: a systematic review. Emerg Med J 2021;38:387-93.
  21. Tsang BKT, Chen ASK, Paine M. Acute evaluation of the acute vestibular syndrome: differentiating posterior circulation stroke from acute peripheral vestibulopathies. Intern Med J 2017;47:1352-60.
  22. Venhovens J, Meulstee J, Verhagen WI. Acute vestibular syndrome: a critical review and diagnostic algorithm concerning the clinical differentiation of peripheral versus central aetiologies in the emergency department. J Neurol 2016;263:2151-7.
  23. Kerber KA, Brown DL, Lisabeth LD, Smith MA, Morgenstern LB. Stroke among patients with dizziness, vertigo, and imbalance in the emergency department: a population-based study. Stroke 2006;37:2484-7.
  24. Kim JS, Lee H. Vertigo due to posterior circulation stroke. Semin Neurol 2013;33:179-84.
  25. Hoyer C, Szabo K. Pitfalls in the Diagnosis of Posterior Circulation Stroke in the Emergency Setting. Front Neurol 2021;12:682827.
  26. Erkelens DC, Rutten FH, Wouters LT, Dolmans LS, de Groot E, Damoiseaux RA, et al. Accuracy of telephone triage in patients suspected of transient ischaemic attack or stroke: a cross-sectional study. BMC Fam Pract 2020;21:256.
  27. Dolmans LS, Rutten F, Bartelink MEL, van Dijk EJ, Nederkoorn PJ, Kappelle J, et al. Serum biomarkers in patients suspected of transient ischaemic attack in primary care: a diagnostic accuracy study. BMJ Open 2019a;9:e031774.
  28. Amort M, Fluri F, Schafer J, Weisskopf F, Katan M, Burow A, et al. Transient ischemic attack versus transient ischemic attack mimics: frequency, clinical characteristics and outcome. Cerebrovasc Dis 2011;32:57-64.
  29. Ferro JM, Falcao I, Rodrigues G, Canhao P, Melo TP, Oliveira V, et al. Diagnosis of transient ischemic attack by the nonneurologist. A validation study. Stroke 1996;27:2225-9.
  30. Kraaijeveld CL, Van Gijn J, Schouten HJ, Staal A. Interobserver agreement for the diagnosis of transient ischemic attacks. Stroke 1984;15:723-5.
  31. Koudstaal PJ, Van Gijn J, Staal A, Duivenvoorden HJ, Gerritsma JG, Kraaijeveld CL. Diagnosis of transient ischemic attacks: improvement of interobserver agreement by a check-list in ordinary language. Stroke 1986;17:723-8.
  32. Dolmans LS, Rutten FH. Praktische aanbevelingen voor de diagnostiek van een TIA. Huisart Wet 2020;63.
  33. Scheinberg P. Transient ischemic attacks: an update. J Neurol Sci 1991;101:133-40.
  34. Howard G, Evans GW, Thomas JL, Ryu JE, Kahl FR, Crouse JR. Reevaluation of transient ischemic attacks as a risk factor for early mortality. Stroke 1991;22:582-5.
  35. Autret A, Pourcelot L, Saudeau D, Marchal C, Bertrand P, De Boisvilliers S. Stroke risk in patients with carotid stenosis. Lancet 1987;1:888-90.
  36. Behar S, Tanne D, Abinader E, Agmon J, Barzilai J, Friedman Y, et al. Cerebrovascular accident complicating acute myocardial infarction: incidence, clinical significance and short- and longterm mortality rates. The SPRINT Study Group. Am J Med 1991;91:45-50.
  37. Wolf PA, Abbott RD, Kannel WB. Atrial fibrillation as an independent risk factor for stroke: the Framingham Study. Stroke 1991;22:983-8.
  38. Marini C, De Santis F, Sacco S, Russo T, Olivieri L, Totaro R, et al. Contribution of atrial fibrillation to incidence and outcome of ischemic stroke: results from a population-based study. Stroke 2005;36:1115-9.
  39. Miller VT, Rothrock JF, Pearce LA, Feinberg WM, Hart RG, Anderson DC. Ischemic stroke in patients with atrial fibrillation: effect of aspirin according to stroke mechanism. Stroke Prevention in Atrial Fibrillation Investigators. Neurology 1993;43:32-6.
  40. Bogousslavsky J, Van Melle G, Regli F, Kappenberger L. Pathogenesis of anterior circulation stroke in patients with nonvalvular atrial fibrillation: the Lausanne Stroke Registry. Neurology 1990;40:1046-50.
  41. Adelborg K, Szépligeti SK, Holland-Bill L, Ehrenstein V, Horváth-Puhó E, Henderson VW, et al. Migraine and risk of cardiovascular diseases: Danish population based matched cohort study. Bmj 2018;360:k96.
  42. Mahmoud AN, Mentias A, Elgendy AY, Qazi A, Barakat AF, Saad M, et al. Migraine and the risk of cardiovascular and cerebrovascular events: a meta-analysis of 16 cohort studies including 1 152 407 subjects. BMJ Open 2018;8:e020498.
  43. Pulsinelli W. Pathophysiology of acute ischaemic stroke. Lancet 1992;339:533-6.
  44. Wise RJ, Bernardi S, Frackowiak RS, Legg NJ, Jones T. Serial observations on the pathophysiology of acute stroke. The transition from ischaemia to infarction as reflected in regional oxygen extraction. Brain 1983;106 (Pt 1):197-222.
  45. Buikema H, Van Gilst WH. Fysiologische rol van endotheel. Hart bulletin 1992;23:215-20.
  46. Anonymus. Treatment for stroke? Lancet 1991;337:1129-31.
  47. Treadwell SD, Thanvi B, Robinson TG. Stroke in pregnancy and the puerperium. Postgrad Med J 2008;84:238-45.
  48. Rouvroije VJH, Raupp SFA, Sluzewski M. Plotselinge ernstige hoofdpijn niet altijd onschuldig. ‘Thunderclap headache’ door reversibele cerebrale vasoconstrictie. Ned Tijdschr Geneeskd 2011;155:A3184.
  49. Ariesen MJ, Claus SP, Rinkel GJE, Algra A. Risk factors for intracerebral hemorrhage in the general population: a systematic review. Stroke 2003;34:2060-5.
  50. Pozzi M, Roccatagliata D, Sterzi R. Drug abuse and intracranial hemorrhage. Neurol Sci 2008;29 Suppl 2:S269-S270.
  51. Franke CL, Blokstra A. Beroerte: hoe zijn preventie en zorg georganiseerd? Nationaal Kompas Volksgezondheid. (2011a).
  52. Langhorne P, Bernhardt J, Kwakkel G. Stroke rehabilitation. Lancet 2011;377:1693-702.
  53. Kwakkel G, Kollen B, Twisk J. Impact of time on improvement of outcome after stroke. Stroke 2006b;37:2348-53.
  54. Kwakkel G, Kollen BJ. Predicting activities after stroke: what is clinically relevant? Int J Stroke 2013;8:25-32.
  55. Van Straten A, Reitsma JB, Limburg M, Van den Bos GA, De Haan RJ. Impact of stroke type on survival and functional health. Cerebrovasc Dis 2001;12:27-33.
  56. Van Asch CJ, Luitse MJ, Rinkel GJ, Van der Tweel I, Algra A, Klijn CJ. Incidence, case fatality, and functional outcome of intracerebral haemorrhage over time, according to age, sex, and ethnic origin: a systematic review and meta-analysis. Lancet Neurol 2010;9:167-76.
  57. Warlow C. Secondary prevention of stroke. Lancet 1992;339:724-7.
  58. Appelros P, Nydevik I, Viitanen M. Poor outcome after first-ever stroke: predictors for death, dependency, and recurrent stroke within the first year. Stroke 2003;34:122-6.
  59. Eriksson SE, Olsson JE. Survival and recurrent strokes in patients with different subtypes of stroke: a fourteen-year follow-up study. Cerebrovasc Dis 2001;12:171-80.
  60. Giles MF, Rothwell PM. Risk of stroke early after transient ischaemic attack: a systematic review and meta-analysis. Lancet Neurol 2007;6:1063-72.
  61. Kleindorfer D, Panagos P, Pancioli A, Khoury J, Kissela B, Woo D, et al. Incidence and short-term prognosis of transient ischemic attack in a population-based study. Stroke 2005;36:720-3.
  62. Coull AJ, Lovett JK, Rothwell PM. Population based study of early risk of stroke after transient ischaemic attack or minor stroke: implications for public education and organisation of services. BMJ 2004;328:326.
  63. Gattellari M, Goumas C, Garden F, Worthington JM. Relative survival after transient ischaemic attack: results from the Program of Research Informing Stroke Management (PRISM) study. Stroke 2012;43:79-85.
  64. Van Cranenburgh B. Neurowetenschappen, een overzicht. Maarssen: Elsevier/De Tijdstroom, 1998.
  65. Wade DT, Hewer RL, David RM, Enderby PM. Aphasia after stroke: natural history and associated deficits. J Neurol Neurosurg Psychiatry 1986;49:11-6.
  66. Dickey L, Kagan A, Lindsay MP, Fang J, Rowland A, Black S. Incidence and profile of inpatient stroke-induced aphasia in Ontario, Canada. Arch Phys Med Rehabil 2010;91:196-202.
  67. El Hachioui H, Lingsma HF, Van de Sandt-Koenderman MW, Dippel DW, Koudstaal PJ, Visch-Brink EG. Long-term prognosis of aphasia after stroke. J Neurol Neurosurg Psychiatry 2013;84:310-5.
  68. Vermeer SE, Koudstaal PJ, Oudkerk M, Hofman A, Breteler MMB. Prevalence and risk factors of silent brain infarcts in the population-based Rotterdam Scan Study. Stroke 2002;33:21-5.
  69. Flamand-Roze C, Cauquil-Michon C, Denier C. Tools and early management of language and swallowing disorders in acute stroke patients. Curr Neurol Neurosci Rep 2012;12:34-41.
  70. Dumoulin C, Korner-Bitensky N, Tannenbaum C. Urinary incontinence after stroke: does rehabilitation make a difference? A systematic review of the effectiveness of behavioral therapy. Top Stroke Rehabil 2005;12:66-76.
  71. Harari D, Coshall C, Rudd AG, Wolfe CDA. New-onset fecal incontinence after stroke: prevalence, natural history, risk factors, and impact. Stroke 2003;34:144-50.
  72. Carlsson GE, Moller A, Blomstrand C. Consequences of mild stroke in persons < 75 years -- a 1-year follow-up. Cerebrovasc Dis 2003;16:383-8.
  73. Glader EL, Stegmayr B, Asplund K. Poststroke fatigue: a 2-year follow-up study of stroke patients in Sweden. Stroke 2002;33:1327-33.
  74. Van der Werf SP, Van den Broek HL, Anten HW, Bleijenberg G. Experience of severe fatigue long after stroke and its relation to depressive symptoms and disease characteristics. Eur Neurol 2001;45:28-33.
  75. McGeough E, Pollock A, Smith LN, Dennis M, Sharpe M, Lewis S, et al. Interventions for post-stroke fatigue. Cochrane Database Syst Rev 2009;CD007030.
  76. Zedlitz AMEE, Rietveld TCM, Geurts AC, Fasotti L. Cognitive and graded activity training can alleviate persistent fatigue after stroke: a randomized, controlled trial. Stroke 2012;43:1046-51.
  77. Pendlebury ST, Rothwell PM. Prevalence, incidence, and factors associated with pre-stroke and post-stroke dementia: a systematic review and meta-analysis. Lancet Neurol 2009;8:1006-18.
  78. Tatemichi TK, Desmond DW, Stern Y, Paik M, Sano M, Bagiella E. Cognitive impairment after stroke: frequency, patterns, and relationship to functional abilities. J Neurol Neurosurg Psychiatry 1994;57:202-7.
  79. Madureira S, Guerreiro M, Ferro JM. Dementia and cognitive impairment three months after stroke. Eur J Neurol 2001;8:621-7.
  80. Jaillard A, Naegele B, Trabucco-Miguel S, LeBas JF, Hommel M. Hidden dysfunctioning in subacute stroke. Stroke 2009;40:2473-9.
  81. Gottesman RF, Hillis AE. Predictors and assessment of cognitive dysfunction resulting from ischaemic stroke. Lancet Neurol 2010;9:895-905.
  82. Cicerone KD, Dahlberg C, Malec JF, Langenbahn DM, Felicetti T, Kneipp S, et al. Evidence-based cognitive rehabilitation: updated review of the literature from 1998 through 2002. Arch Phys Med Rehabil 2005;86:1681-92.
  83. Lincoln NB, Majid MJ, Weyman N. Cognitive rehabilitation for attention deficits following stroke. Cochrane Database Syst Rev 2000;CD002842.
  84. Nair RD, Lincoln NB. Cognitive rehabilitation for memory deficits following stroke. Cochrane Database Syst Rev 2007;CD002293.
  85. Herrmann N, Black SE, Lawrence J, Szekely C, Szalai JP. The Sunnybrook Stroke Study: a prospective study of depressive symptoms and functional outcome. Stroke 1998;29:618-24.
  86. Bhogal SK, Teasell R, Foley N, Speechley M. Lesion location and poststroke depression: systematic review of the methodological limitations in the literature. Stroke 2004;35:794-802.
  87. Paolucci S, Antonucci G, Pratesi L, Traballesi M, Grasso MG, Lubich S. Poststroke depression and its role in rehabilitation of inpatients. Arch Phys Med Rehabil 1999;80:985-90.
  88. Schmid AA, Kroenke K, Hendrie HC, Bakas T, Sutherland JM, Williams LS. Poststroke depression and treatment effects on functional outcomes. Neurology 2011;76:1000-5.
  89. Chemerinski E, Robinson RG, Kosier JT. Improved recovery in activities of daily living associated with remission of poststroke depression. Stroke 2001;32:113-7.
  90. Saxena SK, Ng TP, Koh G, Yong D, Fong NP. Is improvement in impaired cognition and depressive symptoms in post-stroke patients associated with recovery in activities of daily living? Acta Neurol Scand 2007;115:339-46.
  91. Hackett ML, Anderson CS, House A, Xia J. Interventions for treating depression after stroke. Cochrane Database Syst Rev 2008;CD003437.
  92. Van Heugten C, Rasquin S, Winkens I, Beusmans G, Verhey F. Checklist for cognitive and emotional consequences following stroke (CLCE-24): development, usability and quality of the self-report version. Clin Neurol Neurosurg 2007;109:257-62.
  93. Moran GM, Fletcher B, Feltham MG, Calvert M, Sackley C, Marshall T. Fatigue, psychological and cognitive impairment following transient ischaemic attack and minor stroke: a systematic review. Eur J Neurol 2014;21:1258-67.
  94. Turner GM, Calvert M, Feltham MG, Ryan R, Marshall T. Ongoing impairments following transient ischaemic attack: retrospective cohort study. Eur J Neurol 2016;23:1642-50.
  95. Van Rooij FG, Schaapsmeerders P, Maaijwee NA, Van Duijnhoven DA, De Leeuw FE, Kessels RP, et al. Persistent cognitive impairment after transient ischemic attack. Stroke 2014;45:2270-4.
  96. Stroke Unit Trialists’ Collaboration. Organised inpatient (stroke unit) care for stroke. Cochrane Database Syst Rev 2007;CD000197.
  97. Saposnik G, Kapral MK, Coutts SB, Fang J, Demchuk AM, Hill MD. Do all age groups benefit from organized inpatient stroke care? Stroke 2009;40:3321-7.
  98. Xian Y, Holloway RG, Chan PS, Noyes K, Shah MN, Ting HH, et al. Association between stroke center hospitalization for acute ischemic stroke and mortality. JAMA 2011;305:373-80.
  99. Seenan P, Long M, Langhorne P. Stroke units in their natural habitat: systematic review of observational studies. Stroke 2007;38:1886-92.
  100. O’Rourke K, Walsh C. Impact of stroke units on mortality: a Bayesian analysis. Eur J Neurol 2010;17:247-51.
  101. Langhorne P, Dennis MS. Stroke units: the next 10 years. Lancet 2004;363:834-5.
  102. Stam J, Koudstaal PJ, Franke CL, Kappelle LJ, Boiten J. Trombolyse voor het herseninfarct: het einde van het begin. Ned Tijdschr Geneeskd 2000;144:1028-32.
  103. Kappelle LJ, Frijns CJ. Behandeling van patiënten met een TIA of een herseninfarct. Ned Tijdschr Geneeskd 2002;146:1678-81.
  104. Limburg M, Beusmans GHMI, Courlander J, Edelbroek M, Franke-Barendse B, van Gorp E, et al. CVA-zorg in kaart gebracht. Med Contact 2010;65:404-6.
  105. Boode B, Welzen V, Franke C, van Oostenbrugge R. Estimating the number of stroke patients eligible for thrombolytic treatment if delay could be avoided. Cerebrovasc Dis 2007;23:294-8.
  106. NVN. Herseninfarct en hersenbloeding (2021). Ga naar bron: NVN. Herseninfarct en hersenbloeding (2021).
  107. Hankey GJ. Long-term outcome after ischaemic stroke/transient ischaemic attack. Cerebrovasc Dis 2003;16 Suppl 1:14-9.
  108. Rothwell PM, Giles MF, Chandratheva A, Marquardt L, Geraghty O, Redgrave JNE et al. Effect of urgent treatment of transient ischaemic attack and minor stroke on early recurrent stroke (EXPRESS study): a prospective population-based sequential comparison. Lancet 2007;370:1432-42.
  109. Verburg AFE, Stirbu-Wagner I, Wiersma T, Korevaar J. Secundaire preventie na een beroerte. Huisart Wet 2013;12.
  110. Klijn CJ, Kappelle LJ, Tulleken CA, Van Gijn J. Symptomatic carotid artery occlusion. A reappraisal of hemodynamic factors. Stroke 1997;28:2084-93.
  111. Fluri F, Engelter S, Lyrer P. Extracranial-intracranial arterial bypass surgery for occlusive carotid artery disease. Cochrane Database Syst Rev 2010;CD005953.
  112. Powers WJ, Clarke WR, Grubb RLJ, Videen TO, Adams HPJ, Derdeyn CP. Extracranial-intracranial bypass surgery for stroke prevention in hemodynamic cerebral ischemia: the Carotid Occlusion Surgery Study randomized trial. JAMA 2011;306:1983-92.
  113. Langhorne P, Wagenaar R, Partridge C. Physiotherapy after stroke: more is better? Physiother Res Int 1996;1:75-88.
  114. Kwakkel G, Wagenaar RC, Koelman TW, Lankhorst GJ, Koetsier JC. Effects of intensity of rehabilitation after stroke. A research synthesis. Stroke 1997;28:1550-6.
  115. Craig LE, Bernhardt J, Langhorne P, Wu O. Early mobilization after stroke: an example of an individual patient data meta-analysis of a complex intervention. Stroke 2010;41:2632-6.
  116. Kwakkel G. Impact of intensity of practice after stroke: issues for consideration. Disabil Rehabil 2006a;28:823-30.
  117. Kwakkel G, Van Peppen R, Wagenaar RC, Wood Dauphinee S, Richards C, Ashburn A, et al. Effects of augmented exercise therapy time after stroke: a meta-analysis. Stroke 2004;35:2529-39.
  118. Veerbeek JM, Koolstra M, Ket JCF, Van Wegen EEH, Kwakkel G. Effects of augmented exercise therapy on outcome of gait and gait-related activities in the first 6 months after stroke: a meta-analysis. Stroke 2011;42:3311-5.
  119. Langhorne P, Coupar F, Pollock A. Motor recovery after stroke: a systematic review. Lancet Neurol 2009;8:741-54.
  120. Legg LA, Drummond AE, Langhorne P. Occupational therapy for patients with problems in activities of daily living after stroke. Cochrane Database Syst Rev 2006;CD003585.
  121. Legg L, Drummond A, Leonardi-Bee J, Gladman JRF, Corr S, Donkervoort M, et al. Occupational therapy for patients with problems in personal activities of daily living after stroke: systematic review of randomised trials. BMJ 2007;335:922.
  122. Walker MF, Leonardi-Bee J, Bath P, Langhorne P, Dewey M, Corr S, et al. Individual patient data meta-analysis of randomized controlled trials of community occupational therapy for stroke patients. Stroke 2004;35:2226-32.
  123. Van de Port IGL, Kwakkel G, Van Wijk I, Lindeman E. Susceptibility to deterioration of mobility long-term after stroke: a prospective cohort study. Stroke 2006;37:167-71.
  124. Brady MC, Kelly H, Godwin J, Enderby P. Speech and language therapy for aphasia following stroke. Cochrane Database Syst Rev 2012;5:CD000425.
  125. Robey RR. A meta-analysis of clinical outcomes in the treatment of aphasia. J Speech Lang Hear Res 1998;41:172-87.
  126. Mackenzie C, Lowit A. Behavioural intervention effects in dysarthria following stroke: communication effectiveness, intelligibility and dysarthria impact. Int J Lang Commun Disord 2007;42:131-53.
  127. Bowen A, Hesketh A, Patchick E, Young A, Davies L, Vail A, et al. Effectiveness of enhanced communication therapy in the first four months after stroke for aphasia and dysarthria: a randomised controlled trial. BMJ 2012;345:e4407.
  128. Carnaby G, Hankey GJ, Pizzi J. Behavioural intervention for dysphagia in acute stroke: a randomised controlled trial. Lancet Neurol 2006;5:31-7.
  129. Meyran D, Cassan P, Avau B, Singletary E, Zideman DA. Stroke Recognition for First Aid Providers: A Systematic Review and Meta-Analysis. Cureus 2020;12:e11386.
  130. Exalto LG, van Doorn S, Erkelens DCA, Smit K, Rutten FH, Kappelle LJ, et al. Call Characteristics of Patients Suspected of Transient Ischemic Attack (TIA) or Stroke During Out-of-Hours Service: A Comparison Between Men and Women. Front Neurol 2021;12:669090.
  131. Pickham D, Valdez A, Demeestere J, Lemmens R, Diaz L, Hopper S, et al. Prognostic Value of BE-FAST vs. FAST to Identify Stroke in a Prehospital Setting. Prehosp Emerg Care 2019;23:195-200.
  132. Celesia GG, Brigell MG, Vaphiades MS. Hemianopic anosognosia. Neurology 1997;49:88-97.
  133. Oosterhuis HJGH. Klinische Neurologie. Houten/Zaventem: Bohn Stafleu Van Loghum, 2000.
  134. Lebedeva ER, Gurary NM, Gilev DV, Christensen AF, Olesen J. Explicit diagnostic criteria for transient ischemic attacks to differentiate it from migraine with aura. Cephalalgia 2018;38:1463-70.
  135. Dolmans LS, Lebedeva ER, Veluponnar D, van Dijk EJ, Nederkoorn PJ, Hoes AW, et al. Diagnostic Accuracy of the Explicit Diagnostic Criteria for Transient Ischemic Attack: A Validation Study. Stroke 2019b;50:2080-5.
  136. Göbel CH, Karstedt SC, Münte TF, Göbel H, Wolfrum S, Lebedeva ER, et al. Explicit Diagnostic Criteria for Transient Ischemic Attacks Used in the Emergency Department Are Highly Sensitive and Specific. Cerebrovasc Dis 2021;50:62-7.
  137. Sandercock P. Recent developments in the diagnosis and management of patients with transient ischaemic attacks and minor ischaemic strokes. Q J Med 1991;78:101-12.
  138. Alblas CL, Beneder PR, Bulens C. Voorbijgaand geheugenverlies (‘transient global amnesia’): aanwijzigingen voor een syndroom van cerebrale veneuze stase. Ned Tijdschr Geneeskd 2006;150:1685-8.
  139. Erkelens CD, Snoek JW. What doctors should not forget about transient global amnesia. Eur J Gen Pract 2010;16:182-5.
  140. Bartsch T, Deuschl G. Transient global amnesia: functional anatomy and clinical implications. Lancet Neurol 2010;9:205-14.
  141. Thijs RD, Bloem BR, Van Dijk JG. Falls, faints, fits and funny turns. J Neurol 2009;256:155-67.
  142. Parry SW, Kenny RA. Drop attacks in older adults: systematic assessment has a high diagnostic yield. J Am Geriatr Soc 2005;53:74-8.
  143. Brantberg K, Ishiyama A, Baloh RW. Drop attacks secondary to superior canal dehiscence syndrome. Neurology 2005;64:2126-8.
  144. Psychogios K, Magoufis G, Safouris A, Kargiotis O, Katsanos AH, Spiliopoulos S, et al. Eligibility for intravenous thrombolysis in acute ischemic stroke patients presenting in the 4.5-9 h window. Neuroradiology 2020;62:733-9.
  145. Thomalla G, Simonsen CZ, Boutitie F, Andersen G, Berthezene Y, Cheng B, et al. MRI-Guided Thrombolysis for Stroke with Unknown Time of Onset. N Engl J Med 2018;379:611-22.
  146. Jadhav AP, Desai SM, Kenmuir CL, Rocha M, Starr MT, Molyneaux BJ, et al. Eligibility for Endovascular Trial Enrollment in the 6- to 24-Hour Time Window: Analysis of a Single Comprehensive Stroke Center. Stroke 2018;49:1015-7.
  147. Barber PA, Zhang J, Demchuk AM, Hill MD, Buchan AM. Why are stroke patients excluded from TPA therapy? An analysis of patient eligibility. Neurology 2001;56:1015-20.
  148. Coutts SB, Modi J, Patel SK, Aram H, Demchuk AM, Goyal M, et al. What causes disability after transient ichemic attack and minor stroke? Results from the CT And MRI in the triage of TIA and minor cerebrovascular events to identify high risk patients (CATCH) study. Stroke 2012;43:3018-22.
  149. Zinkstok SM, Roos YB. Early administration of aspirin in patients treated with alteplase for acute ischaemic stroke: a randomised controlled trial. Lancet 2012;380:731-7.
  150. Oliveira-Filho J, Silva SCS, Trabuco CC, Pedreira BB, Sousa EU, Bacellar A. Detrimental effect of blood pressure reduction in the first 24 hours of acute stroke onset. Neurology 2003;61:1047-51.
  151. Sandset EC, Bath PMW, Boysen G, Jatuzis D, Korv J, Luders S, et al. The angiotensin-receptor blocker candesartan for treatment of acute stroke (SCAST): a randomised, placebo-controlled, double-blind trial. Lancet 2011;377:741-50.
  152. Anderson CS, Huang Y, Arima H, Heeley E, Skulina C, Parsons MW, et al. Effects of early intensive blood pressure-lowering treatment on the growth of hematoma and perihematomal edema in acute intracerebral hemorrhage: the Intensive Blood Pressure Reduction in Acute Cerebral Haemorrhage Trial (INTERACT). Stroke 2010;41:307-12.
  153. Anderson CS, Heeley E, Huang Y, Wang J, Stapf C, Delcourt C, et al. Rapid blood-pressure lowering in patients with acute intracerebral hemorrhage. N Engl J Med 2013;368:2355-65.
  154. Qureshi AI, Palesch YY, Barsan WG, Hanley DF, Hsu CY, Martin RL, et al. Intensive blood-pressure lowering in patients with acute cerebral hemorrhage. N Engl J Med 2016;375:1033-43.
  155. Robinson TG, Potter JF, Ford GA, Bulpitt CJ, Chernova J, Jagger C, et al. Effects of antihypertensive treatment after acute stroke in the Continue or Stop Post-Stroke Antihypertensives Collaborative Study (COSSACS): a prospective, randomised, open, blinded-endpoint trial. Lancet Neurol 2010;9:767-75.
  156. Lees KR, Bluhmki E, von Kummer R, Brott TG, Toni D, Grotta JC, et al. Time to treatment with intravenous alteplase and outcome in stroke: an updated pooled analysis of ECASS, ATLANTIS, NINDS, and EPITHET trials. Lancet 2010;375:1695-703.
  157. Sandercock P, Wardlaw JM, Lindley RI, Dennis M, Cohen G, Murray G, et al. The benefits and harms of intravenous thrombolysis with recombinant tissue plasminogen activator within 6 h of acute ischaemic stroke (the third international stroke trial [IST-3]): a randomised controlled trial. Lancet 2012;379:2352-63.
  158. Wardlaw JM, Murray V, Berge E, Del Zoppo G, Sandercock P, Lindley RL, et al. Recombinant tissue plasminogen activator for acute ischaemic stroke: an updated systematic review and meta-analysis. Lancet 2012;379:2364-72.
  159. Meseguer E, Mazighi M, Labreuche J, Arnaiz C, Cabrejo L, Slaoui T, et al. Outcomes of intravenous recombinant tissue plasminogen activator therapy according to gender: a clinical registry study and systematic review. Stroke 2009;40:2104-10.
  160. Bluhmki E, Chamorro A, Davalos A, Machnig T, Sauce C, Wahlgren N, et al. Stroke treatment with alteplase given 3.0-4.5 h after onset of acute ischaemic stroke (ECASS III): additional outcomes and subgroup analysis of a randomised controlled trial. Lancet Neurol 2009;8:1095-102.
  161. Hacke W, Donnan G, Fieschi C, Kaste M, Von Kummer R, Broderick JP, et al. Association of outcome with early stroke treatment: pooled analysis of ATLANTIS, ECASS, and NINDS rt-PA stroke trials. Lancet 2004;363:768-74.
  162. Wahlgren N, Ahmed N, Eriksson N, Aichner F, Bluhmki E, Davalos A, et al. Multivariable analysis of outcome predictors and adjustment of main outcome results to baseline data profile in randomized controlled trials: Safe Implementation of Thrombolysis in Stroke-MOnitoring STudy (SITS-MOST). Stroke 2008;39:3316-22.
  163. Campbell BCV, Ma H, Ringleb PA, Parsons MW, Churilov L, Bendszus M, et al. Extending thrombolysis to 4.5-9 h and wake-up stroke using perfusion imaging: a systematic review and meta-analysis of individual patient data. Lancet 2019.
  164. Ma H, Campbell BCV, Parsons MW, Churilov L, Levi CR, Hsu C, et al. Thrombolysis Guided by Perfusion Imaging up to 9 Hours after Onset of Stroke. N Engl J Med 2019;380:1795-803.
  165. Ringleb P, Bendszus M, Bluhmki E, Donnan G, Eschenfelder C, Fatar M, et al. Extending the time window for intravenous thrombolysis in acute ischemic stroke using magnetic resonance imaging-based patient selection. Int J Stroke 2019;14:483-90.
  166. Davis SM, Donnan GA, Parsons MW, Levi C, Butcher KS, Peeters A, et al. Effects of alteplase beyond 3 h after stroke in the Echoplanar Imaging Thrombolytic Evaluation Trial (EPITHET): a placebo-controlled randomised trial. Lancet Neurol 2008;7:299-309.
  167. Thomalla G, Boutitie F, Ma H, Koga M, Ringleb P, Schwamm LH, et al. Intravenous alteplase for stroke with unknown time of onset guided by advanced imaging: systematic review and meta-analysis of individual patient data. Lancet 2020;396:1574-84.
  168. Broderick JP, Palesch YY, Demchuk AM, Yeatts SD, Khatri P, Hill MD, et al. Endovascular therapy after intravenous t-PA versus t-PA alone for stroke. N Engl J Med 2013;368:893-903.
  169. Ciccone A, Valvassori L, Nichelatti M, Sgoifo A, Ponzio M, Sterzi R, et al. Endovascular treatment for acute ischemic stroke. N Engl J Med 2013;368:904-13.
  170. Kidwell CS, Jahan R, Gornbein J, Alger JR, Nenov V, Ajani Z, et al. A trial of imaging selection and endovascular treatment for ischemic stroke. N Engl J Med 2013;368:914-23.
  171. Berkhemer OA, Fransen PS, Beumer D, van den Berg LA, Lingsma HF, Yoo AJ, et al. A randomized trial of intraarterial treatment for acute ischemic stroke. N Engl J Med 2015;372:11-20.
  172. Goyal M, Menon BK, van Zwam WH, Dippel DW, Mitchell PJ, Demchuk AM, et al. Endovascular thrombectomy after large-vessel ischaemic stroke: a meta-analysis of individual patient data from five randomised trials. Lancet 2016;387:1723-31.
  173. Jovin TG, Chamorro A, Cobo E, de Miquel MA, Molina CA, Rovira A, et al. Thrombectomy within 8 hours after symptom onset in ischemic stroke. N Engl J Med 2015;372:2296-306.
  174. Saver JL, Goyal M, van der Lugt A, Menon BK, Majoie CB, Dippel DW, et al. Time to Treatment With Endovascular Thrombectomy and Outcomes From Ischemic Stroke: A Meta-analysis. Jama 2016;316:1279-88.
  175. Stroke Foundation. Clinical Guidelines for Stroke Management (2021). Ga naar bron: Stroke Foundation. Clinical Guidelines for Stroke Management (2021).
  176. Campbell BC, Mitchell PJ, Kleinig TJ, Dewey HM, Churilov L, Yassi N, et al. Endovascular therapy for ischemic stroke with perfusion-imaging selection. N Engl J Med 2015;372:1009-18.
  177. Goyal M, Demchuk AM, Menon BK, Eesa M, Rempel JL, Thornton J, et al. Randomized assessment of rapid endovascular treatment of ischemic stroke. N Engl J Med 2015;372:1019-30.
  178. Saver JL, Goyal M, Bonafe A, Diener HC, Levy EI, Pereira VM, et al. Stent-retriever thrombectomy after intravenous t-PA vs. t-PA alone in stroke. N Engl J Med 2015;372:2285-95.
  179. Bracard S, Ducrocq X, Mas JL, Soudant M, Oppenheim C, Moulin T, et al. Mechanical thrombectomy after intravenous alteplase versus alteplase alone after stroke (THRACE): a randomised controlled trial. Lancet Neurol 2016;15:1138-47.
  180. Mocco J, Zaidat OO, von Kummer R, Yoo AJ, Gupta R, Lopes D, et al. Aspiration Thrombectomy After Intravenous Alteplase Versus Intravenous Alteplase Alone. Stroke 2016;47:2331-8.
  181. Muir KW, Ford GA, Messow CM, Ford I, Murray A, Clifton A, et al. Endovascular therapy for acute ischaemic stroke: the Pragmatic Ischaemic Stroke Thrombectomy Evaluation (PISTE) randomised, controlled trial. J Neurol Neurosurg Psychiatry 2017;88:38-44.
  182. Albers GW, Marks MP, Kemp S, Christensen S, Tsai JP, Ortega-Gutierrez S, et al. Thrombectomy for Stroke at 6 to 16 Hours with Selection by Perfusion Imaging. N Engl J Med 2018;378:708-18.
  183. Nogueira RG, Jadhav AP, Haussen DC, Bonafe A, Budzik RF, Bhuva P, et al. Thrombectomy 6 to 24 Hours after Stroke with a Mismatch between Deficit and Infarct. New England Journal of Medicine 2018;378:11-21.
  184. De Keyser J, Gdovinova Z, Uyttenboogaart M, Vroomen PC, Luijckx GJ. Intravenous alteplase for stroke: beyond the guidelines and in particular clinical situations. Stroke 2007;38:2612-8.
  185. Sylaja PN, Dzialowski I, Krol A, Roy J, Federico P, Demchuk AM. Role of CT angiography in thrombolysis decision-making for patients with presumed seizure at stroke onset. Stroke 2006;37:915-7.
  186. Anonymus. The International Stroke Trial (IST): a randomised trial of aspirin, subcutaneous heparin, both, or neither among 19435 patients with acute ischaemic stroke. International Stroke Trial Collaborative Group. Lancet 1997b;349:1569-81.
  187. Anonymus. CAST: randomised placebo-controlled trial of early aspirin use in 20,000 patients with acute ischaemic stroke. CAST (Chinese Acute Stroke Trial) Collaborative Group. Lancet 1997a;349:1641-9.
  188. Chen ZM, Sandercock P, Pan HC, Counsell C, Collins R, Liu LS, et al. Indications for early aspirin use in acute ischemic stroke: a combined analysis of 40 000 randomized patients from the chinese acute stroke trial and the international stroke trial. On behalf of the CAST and IST collaborative groups. Stroke 2000;31:1240-9.
  189. Anonymus. Collaborative meta-analysis of randomised trials of antiplatelet therapy for prevention of death, myocardial infarction, and stroke in high risk patients. BMJ 2002;324:71-86.
  190. Sandercock PAG, Counsell C, Gubitz GJ, Tseng MC. Antiplatelet therapy for acute ischaemic stroke. Cochrane Database Syst Rev 2008;CD000029.
  191. Patrignani P, Filabozzi P, Patrono C. Selective cumulative inhibition of platelet thromboxane production by low-dose aspirin in healthy subjects. J Clin Invest 1982;69:1366-72.
  192. Galvin R, Geraghty C, Motterlini N, Dimitrov BD, Fahey T. Prognostic value of the ABCD(2) clinical prediction rule: a systematic review and meta-analysis. Fam Pract 2011;28:366-76.
  193. Johnston SC, Rothwell PM, Nguyen-Huynh MN, Giles MF, Elkins JS, Bernstein AL, et al. Validation and refinement of scores to predict very early stroke risk after transient ischaemic attack. Lancet 2007;369:283-92.
  194. Dippel DWJ. TIA: wel reden voor spoedopname. Ned Tijdschr Geneeskd 2011;155:A3133.
  195. Giles MF, Rothwell PM. Systematic review and pooled analysis of published and unpublished validations of the ABCD and ABCD2 transient ischemic attack risk scores. Stroke 2010;41:667-73.
  196. Sanders LM, Srikanth VK, Blacker DJ, Jolley DJ, Cooper KA, Phan TG. Performance of the ABCD2 score for stroke risk post TIA: meta-analysis and probability modelling. Neurology 2012;971-80.
  197. Wind AW, Van der Werf GTh. Huisartsgeneeskunde voor ouderen (1): regie over complexe zorg vereist zorgplan. Huisarts Wet 2007;126-7.
  198. De Haan R, Limburg M, Schuling J, Broeshart J, Jonkers L, Van Zuylen P. Klinimetrische evaluatie van de Barthel Index. Ned Tijdschr Geneeskd 1993;137:917-21.
  199. Huybrechts KF, Caro JJ. The Barthel Index and modified Rankin Scale as prognostic tools for long-term outcomes after stroke: a qualitative review of the literature. Curr Med Res Opin 2007;23:1627-36.
  200. Shi D, Chen X, Li Z. Diagnostic test accuracy of the Montreal Cognitive Assessment in the detection of post-stroke cognitive impairment under different stages and cutoffs: a systematic review and meta-analysis. Neurol Sci 2018;39:705-16.
  201. Lees R, Selvarajah J, Fenton C, Pendlebury ST, Langhorne P, Stott DJ, et al. Test accuracy of cognitive screening tests for diagnosis of dementia and multidomain cognitive impairment in stroke. Stroke 2014;45:3008-18.
  202. Chen X, Han Y, Zhou J, Ma M, Liu X. Diagnostic accuracy of cognitive screening tools under different neuropsychological definitions for poststroke cognitive impairment. Brain Behav 2020;10:e01671.
  203. Khaw J, Subramaniam P, Abd Aziz NA, Ali Raymond A, Wan Zaidi WA, Ghazali SE. Current Update on the Clinical Utility of MMSE and MoCA for Stroke Patients in Asia: A Systematic Review. Int J Environ Res Public Health 2021;18.
  204. Kappelle LJ, Adams HPJ, Heffner ML, Torner JC, Gomez F, Biller J. Prognosis of young adults with ischemic stroke. A long-term follow-up study assessing recurrent vascular events and functional outcome in the Iowa Registry of Stroke in Young Adults. Stroke 1994;25:1360-5.
  205. Musolino R, La Spina P, Granata A, Gallitto G, Leggiadro N, Carerj S, et al. Ischaemic stroke in young people: a prospective and longterm follow-up study. Cerebrovasc Dis 2003;15:121-8.
  206. Neau JP, Ingrand P, Mouille-Brachet C, Rosier MP, Couderq C, Alvarez A, et al. Functional recovery and social outcome after cerebral infarction in young adults. Cerebrovasc Dis 1998;8:296-302.
  207. Vestling M, Tufvesson B, Iwarsson S. Indicators for return to work after stroke and the importance of work for subjective well-being and life satisfaction. J Rehabil Med 2003;35:127-31.
  208. Treger I, Shames J, Giaquinto S, Ring H. Return to work in stroke patients. Disabil Rehabil 2007;29:1397-403.
  209. Saeki S, Ogata H, Okubo T, Takahashi K, Hoshuyama T. Return to work after stroke. A follow-up study. Stroke 1995;26:399-401.
  210. Coronel Instituut voor Arbeid en Gezondheid. Niet-Aangeboren Hersenletsel (NAH) en Arbeidsparticipatie. Multidisciplinaire Richtlijn voor Beoordelen, Behandelen en Begeleiden (2012). Ga naar bron: Coronel Instituut voor Arbeid en Gezondheid. Niet-Aangeboren Hersenletsel (NAH) en Arbeidsparticipatie. Multidisciplinaire Richtlijn voor Beoordelen, Behandelen en Begeleiden (2012).
  211. VRA. NAH en arbeidsparticipatie (2021). Ga naar bron: VRA. NAH en arbeidsparticipatie (2021).
  212. Visser-Meily A, Van Heugten C. Zorg voor de mantelzorg (2004).
  213. Schure LM. Partners van CVA-patiënten: een onderzoek naar de gevolgen van een cerebrovasculair accident voor de partner van de patiënt [proefschrift]. Groningen: Rijksuniversiteit Groningen, 1995.
  214. Berg A, Palomaki H, Lonnqvist J, Lehtihalmes M, Kaste M. Depression among caregivers of stroke survivors. Stroke 2005;36:639-43.
  215. Paul SL, Thrift AG, Donnan GA. Smoking as a crucial independent determinant of stroke. Tob Induc Dis 2004;2:67-80.
  216. Shinton R, Beevers G. Meta-analysis of relation between cigarette smoking and stroke. BMJ 1989;298:789-94.
  217. Wolf PA, D’Agostino RB, Kannel WB, Bonita R, Belanger AJ. Cigarette smoking as a risk factor for stroke. The Framingham Study. JAMA 1988;259:1025-9.
  218. Myint PK, Welch AA, Bingham SA, Luben RN, Wareham NJ, Day NE, et al. Smoking predicts long-term mortality in stroke: the European Prospective Investigation into Cancer (EPIC)-Norfolk prospective population study. Prev Med 2006;42:128-31.
  219. Redfern J, McKevitt C, Dundas R, Rudd AG, Wolfe CD. Behavioral risk factor prevalence and lifestyle change after stroke: a prospective study. Stroke 2000;31:1877-81.
  220. Wendel-Vos GCW, Schuit AJ, Feskens EJM, Boshuizen HC, Verschuren WMM, Saris WHM, et al. Physical activity and stroke. A meta-analysis of observational data. Int J Epidemiol 2004;33:787-98.
  221. Lee CD, Folsom AR, Blair SN. Physical activity and stroke risk: a meta-analysis. Stroke 2003;34:2475-81.
  222. Gordon NF, Gulanick M, Costa F, Fletcher G, Franklin BA, Roth EJ, et al. Physical activity and exercise recommendations for stroke survivors: an American Heart Association scientific statement from the Council on Clinical Cardiology, Subcommittee on Exercise, Cardiac Rehabilitation, and Prevention; the Council on Cardiovascular Nursing; the Council on Nutrition, Physical Activity, and Metabolism; and the Stroke Council. Stroke 2004;35:1230-40.
  223. Patra J, Taylor B, Irving H, Roerecke M, Baliunas D, Mohapatra S, et al. Alcohol consumption and the risk of morbidity and mortality for different stroke types--a systematic review and meta-analysis. BMC Public Health 2010;10:258.
  224. Strazzullo P, D’Elia L, Cairella G, Garbagnati F, Cappuccio FP, Scalfi L. Excess body weight and incidence of stroke: meta-analysis of prospective studies with 2 million participants. Stroke 2010;41:e418-e426.
  225. Calabro RS, Gervasi G, Bramanti P. Male sexual disorders following stroke: an overview. Int J Neurosci 2011;121:598-604.
  226. Korpelainen JT, Nieminen P, Myllyla VV. Sexual functioning among stroke patients and their spouses. Stroke 1999;30:715-9.
  227. Sacco RL, Diener HC, Yusuf S, Cotton D, Ounpuu S, Lawton WA, et al. Aspirin and extended-release dipyridamole versus clopidogrel for recurrent stroke. N Engl J Med 2008;359:1238-51.
  228. Anonymus. A randomised, blinded, trial of clopidogrel versus aspirin in patients at risk of ischaemic events (CAPRIE). CAPRIE Steering Committee. Lancet 1996;348:1329-39.
  229. Kent DM, Thaler DE. Stroke prevention-insights from incoherence. N Engl J Med 2008;359:1287-9.
  230. Diener HC, Bogousslavsky J, Brass LM, Cimminiello C, Csiba L, Kaste M, et al. Aspirin and clopidogrel compared with clopidogrel alone after recent ischaemic stroke or transient ischaemic attack in high-risk patients (MATCH): randomised, double-blind, placebo-controlled trial. Lancet 2004;364:331-7.
  231. Bhatt DL, Fox KAA, Hacke W, Berger PB, Black HR, Boden WE, et al. Clopidogrel and aspirin versus aspirin alone for the prevention of atherothrombotic events. N Engl J Med 2006;354:1706-17.
  232. Benavente OR, Hart RG, McClure LA, Szychowski JM, Coffey CS, Pearce LA et al. Effects of clopidogrel added to aspirin in patients with recent lacunar stroke. N Engl J Med 2012;367:817-25.
  233. Sudlow CL, Mason G, Maurice JB, Wedderburn CJ, Hankey GJ. Thienopyridine derivatives versus aspirin for preventing stroke and other serious vascular events in high vascular risk patients. Cochrane Database Syst Rev 2009;CD001246.
  234. Zuurbier SM, Vermeer SE, Hilkens PHE, Algra A, Roos YBWE. Secundaire preventie met clopidogrel na TIA of herseninfarct. Ned Tijdschr Geneeskd 2013;157:A5836.
  235. Antithrombotic Trialists Collaboration. Collaborative meta-analysis of randomised trials of antiplatelet therapy for prevention of death, myocardial infarction, and stroke in high risk patients. Bmj 2002;324:71-86.
  236. Johnson ES, Lanes SF, Wentworth CE, Satterfield MH, Abebe BL, Dicker LW. A metaregression analysis of the dose-response effect of aspirin on stroke. Arch Intern Med 1999;159:1248-53.
  237. Dutch TIA Trial Study Group. A comparison of two doses of aspirin (30 mg vs. 283 mg a day) in patients after a transient ischemic attack or minor ischemic stroke. N Engl J Med 1991;325:1262.
  238. Kalmann R, Nieuwenhuis HK, De Groot P, Van Gijn J. Effects of low dosis of aspirin, 10 mg and 30 mg daily, on bleeding time, tomboxane production and 6-keto-PGF1[alpha]-excretion in healthy subjects. Tromb Res 1987;45:355-61.
  239. Algra A, Koudstaal PJ, Van Gijn J. Secundaire preventie na cerebrale ischemie: monotherapie met acetylsalicylzuur nog steeds de eerste keus? Ned Tijdschr Geneeskd 1998;142:277.
  240. Halkes PHA, Van Gijn J, Kappelle LJ, Koudstaal PJ, Algra A. Aspirin plus dipyridamole versus aspirin alone after cerebral ischaemia of arterial origin (ESPRIT): randomised controlled trial. Lancet 2006;367:1665-73.
  241. Thijs V, Lemmens R, Fieuws S. Network meta-analysis: simultaneous meta-analysis of common antiplatelet regimens after transient ischaemic attack or stroke. Eur Heart J 2008;29:1086-92.
  242. Halkes PH, Gray LJ, Bath PM, Diener HC, Guiraud-Chaumeil B, Yatsu FM, et al. Dipyridamole plus aspirin versus aspirin alone in secondary prevention after TIA or stroke: a meta-analysis by risk. J Neurol Neurosurg Psychiatry 2008;79:1218-23.
  243. Verro P, Gorelick PB, Nguyen D. Aspirin plus dipyridamole versus aspirin for prevention of vascular events after stroke or TIA: a meta-analysis. Stroke 2008;39:1358-63.
  244. Dippel DW, Maasland L, Halkes P, Kappelle LJ, Koudstaal PJ, Algra A. Prevention with low-dose aspirin plus dipyridamole in patients with disabling stroke. Stroke 2010;41:2684-6.
  245. Diener HC, Cunha L, Forbes C, Sivenius J, Smets P, Lowenthal A. European Stroke Prevention Study. 2. Dipyridamole and acetylsalicylic acid in the secondary prevention of stroke. J Neurol Sci 1996;143:1-13.
  246. Heeg B, Damen J, Van Hout B. Oral antiplatelet therapy in secondary prevention of cardiovascular events: an assessment from the payer’s perspective. Pharmacoeconomics 2007;25:1063-82.
  247. Prasad K, Siemieniuk R, Hao Q, Guyatt G, O'Donnell M, Lytvyn L, et al. Dual antiplatelet therapy with aspirin and clopidogrel for acute high risk transient ischaemic attack and minor ischaemic stroke: a clinical practice guideline. 2018;363:k5130.
  248. Hao Q, Tampi M, O'Donnell M, Foroutan F, Siemieniuk RA, Guyatt G. Clopidogrel plus aspirin versus aspirin alone for acute minor ischaemic stroke or high risk transient ischaemic attack: systematic review and meta-analysis. BMJ 2018;363:k5108.
  249. Kennedy J, Hill MD, Ryckborst KJ, Eliasziw M, Demchuk AM, Buchan AM. Fast assessment of stroke and transient ischaemic attack to prevent early recurrence (FASTER): a randomised controlled pilot trial. Lancet Neurol 2007;6:961-9.
  250. Wang Y, Wang Y, Zhao X, Liu L, Wang D, Wang C, et al. Clopidogrel with aspirin in acute minor stroke or transient ischemic attack. N Engl J Med 2013;369:11-9.
  251. Johnston SC, Easton JD, Farrant M, Barsan W, Conwit RA, Elm JJ, et al. Clopidogrel and Aspirin in Acute Ischemic Stroke and High-Risk TIA. N Engl J Med 2018;379:215-25.
  252. Pan Y, Wang A, Liu G, Zhao X, Meng X, Zhao K, et al. Cost-effectiveness of clopidogrel-aspirin versus aspirin alone for acute transient ischemic attack and minor stroke. J Am Heart Assoc 2014;3:e000912.
  253. Anonymus. Secondary prevention in non-rheumatic atrial fibrillation after transient ischaemic attack or minor stroke. EAFT (European Atrial Fibrillation Trial) Study Group. Lancet 1993;342:1255-62.
  254. Saxena R, Koudstaal P. Anticoagulants versus antiplatelet therapy for preventing stroke in patients with nonrheumatic atrial fibrillation and a history of stroke or transient ischemic attack. Cochrane Database Syst Rev 2004;CD000187.
  255. Anonymus. Optimal oral anticoagulant therapy in patients with nonrheumatic atrial fibrillation and recent cerebral ischemia. The European Atrial Fibrillation Trial Study Group. N Engl J Med 1995a;333:5-10.
  256. De Schryver EL, Algra A, Kappelle LJ, Van Gijn J, Koudstaal PJ. Vitamin K antagonists versus antiplatelet therapy after transient ischaemic attack or minor ischaemic stroke of presumed arterial origin. Cochrane Database Syst Rev 2012;9:CD001342.
  257. Salazar CA, del Aguila D, Cordova EG. Direct thrombin inhibitors versus vitamin k antagonists for preventing cerebral or systemic embolism in people with non-valvular atrial fibrillation. Cochrane Database Syst Rev 2014:CD009893.
  258. Bruins Slot KM, Berge E. Factor xa inhibitors versus vitamin k antagonists for preventing cerebral or systemic embolism in patients with atrial fibrillation. Cochrane Database Syst Rev 2013:CD008980.
  259. Lin L, Lim WS, Zhou HJ, Khoo AL, Tan KT, Chew AP, et al. Clinical and safety outcomes of oral antithrombotics for stroke prevention in atrial fibrillation: a systematic review and network meta-analysis. J Am Med Dir Assoc 2015;16:1103.e1-19.
  260. Diener HC, Connolly SJ, Ezekowitz MD, Wallentin L, Reilly PA, Yang S, et al. Dabigatran compared with warfarin in patients with atrial fibrillation and previous transient ischaemic attack or stroke: a subgroup analysis of the RE-LY trial. Lancet Neurol 2010;9:1157-63.
  261. Hankey GJ, Patel MR, Stevens SR, Becker RC, Breithardt G, Carolei A, et al. Rivaroxaban compared with warfarin in patients with atrial fibrillation and previous stroke or transient ischaemic attack: a subgroup analysis of ROCKET AF. Lancet Neurol 2012;11:315-22.
  262. Easton JD, Lopes RD, Bahit MC, Wojdyla DM, Granger CB, Wallentin L, et al. Apixaban compared with warfarin in patients with atrial fibrillation and previous stroke or transient ischaemic attack: a subgroup analysis of the ARISTOTLE trial. Lancet Neurol 2012;11:503-11.
  263. Wallentin L, Yusuf S, Ezekowitz MD, Alings M, Flather M, Franzosi MG, et al. Efficacy and safety of dabigatran compared with warfarin at different levels of international normalised ratio control for stroke prevention in atrial fibrillation: an analysis of the RE-LY trial. Lancet 2010;376:975-83
  264. Adam SS, McDuffie JR, Ortel TL, Williams JW, Jr. Comparative effectiveness of warfarin and new oral anticoagulants for the management of atrial fibrillation and venous thromboembolism: a systematic review. Ann Intern Med 2012;157:796-807.
  265. Amarenco P, Bogousslavsky J, Callahan A, Goldstein LB, Hennerici M, Rudolph AE, et al. High-dose atorvastatin after stroke or transient ischemic attack. N Engl J Med 2006;355:549-59.
  266. Collins R, Armitage J, Parish S, Sleight P, Peto R. Effects of cholesterol-lowering with simvastatin on stroke and other major vascular events in 20536 people with cerebrovascular disease or other high-risk conditions. Lancet 2004;363:757-67.
  267. Manktelow BN, Potter JF. Interventions in the management of serum lipids for preventing stroke recurrence. Cochrane Database Syst Rev 2009;CD002091.
  268. Vergouwen MDI, De Haan RJ, Vermeulen M, Roos YBWE. Statin treatment and the occurrence of hemorrhagic stroke in patients with a history of cerebrovascular disease. Stroke 2008;39:497-502.
  269. Amarenco P, Labreuche J. Lipid management in the prevention of stroke: review and updated meta-analysis of statins for stroke prevention. Lancet Neurol 2009;8:453-63.
  270. Piepoli MF, Hoes AW, Agewall S, Albus C, Brotons C, Catapano AL, et al. 2016 european guidelines on cardiovascular disease prevention in clinical practice: the sixth joint task force of the european society of cardiology and other societies on cardiovascular disease prevention in clinical practice (constituted by representatives of 10 societies and by invited experts) developed with the special contribution of the european association for cardiovascular prevention & rehabilitation (eacpr). Eur Heart J 2016;37:2315-81.
  271. PROGRESS Collaborative Group. Randomised trial of a perindopril-based blood-pressure-lowering regimen among 6105 individuals with previous stroke or transient ischaemic attack. Lancet 2001;358:1033-41.
  272. Yusuf S, Diener HC, Sacco RL, Cotton D, Ounpuu S, Lawton WA, et al. Telmisartan to prevent recurrent stroke and cardiovascular events. N Engl J Med 2008;359:1225-37.
  273. Ovbiagele B, Diener HC, Yusuf S, Martin RH, Cotton D, Vinisko R, et al. Level of systolic blood pressure within the normal range and risk of recurrent stroke. JAMA 2011;306:2137-44.
  274. Lakhan SE, Sapko MT. Blood pressure lowering treatment for preventing stroke recurrence: a systematic review and meta-analysis. Int Arch Med 2009;2:30.
  275. Debette S, Leys D. Cervical-artery dissections: predisposing factors, diagnosis, and outcome. Lancet Neurol 2009;8:668-78.
  276. Lyrer P, Engelter S. Antithrombotic drugs for carotid artery dissection. Cochrane Database Syst Rev 2010;CD000255.
  277. Kennedy F, Lanfranconi S, Hicks C, Reid J, Gompertz P, Price C, et al. Antiplatelets vs anticoagulation for dissection: CADISS nonrandomized arm and meta-analysis. Neurology 2012;79:686-9.
  278. Béjot Y, Cordonnier C, Durier J, Aboa-Eboulé C, Rouaud O, Giroud M. Intracerebral haemorrhage profiles are changing: results from the Dijon population-based study. Brain 2013;136:658-64.
  279. Cheng B, Li J, Peng L, Wang Y, Sun L, He S, et al. Efficacy and safety of restarting antiplatelet therapy for patients with spontaneous intracranial haemorrhage: A systematic review and meta-analysis. J Clin Pharm Ther 2021;46:957-65.
  280. RESTART Collaboration. Effects of antiplatelet therapy after stroke due to intracerebral haemorrhage (RESTART): a randomised, open-label trial. Lancet 2019;393:2613-23.
  281. Al-Shahi Salman R, Dennis MS, Sandercock PAG, Sudlow CLM, Wardlaw JM, Whiteley WN, et al. Effects of Antiplatelet Therapy After Stroke Caused by Intracerebral Hemorrhage: Extended Follow-up of the RESTART Randomized Clinical Trial. JAMA Neurol 2021;78:1179-86.
  282. Goldstein LB, Amarenco P, Szarek M, Callahan A, Hennerici M, Sillesen H, et al. Hemorrhagic stroke in the stroke prevention by aggressive reduction in cholesterol levels study. Neurology 2008;70:2364-70.
  283. Westover MB, Bianchi MT, Eckman MH, Greenberg SM. Statin use following intracerebral hemorrhage: a decision analysis. Arch Neurol 2011;68:573-9.
  284. Visseren FL, Lansberg PJ, Erkelens DW, Kastelein JJ. Statinen: mogelijk meer dan alleen verandering van de lipideconcentratie. Ned Tijdschr Geneeskd 2000;144:316-21.
  285. McKinney JS, Kostis WJ. Statin therapy and the risk of intracerebral hemorrhage: a meta-analysis of 31 randomized controlled trials. Stroke 2012;43:2149-56.
  286. Hackam DG, Woodward M, Newby LK, Bhatt DL, Shao M, Smith EE, et al. Statins and intracerebral hemorrhage: collaborative systematic review and meta-analysis. Circulation 2011;124:2233-42.
  287. Huijsman R. Stroke service biedt betere zorg voor CVA-patiënten. Med Contact 2001;48:1765-8.
  288. Minkman MMN, Schouten LMT, Huijsman R, Van Splunteren PT. Integrated care for patients with a stroke in the Netherlands: results and experiences from a national Breakthrough Collaborative Improvement project. Int J Integr Care 2005;5:e14.
  289. Mitchell GK, Brown RM, Erikssen L, Tieman JJ. Multidisciplinary care planning in the primary care management of completed stroke: a systematic review. BMC Fam Pract 2008;9:44.
  290. Kennisnetwerk CVA NL. Deelname stroke services aan Kennisnetwerk CVA NL (2013). Ga naar bron: Kennisnetwerk CVA NL. Deelname stroke services aan Kennisnetwerk CVA NL (2013).
NHG-werkgroep:
Dolmans LS, Hegeman LF, Tjon-A-Tsien MRS, Van den Donk M, Van Noortwijk-Bonga HGC, Verburg-Oorthuizen AFE, Wiersma Tj.
4 gerelateerde lacunes4 gerelateerde onderzoeken